Health Sciences

Centre for Human Genetics and Molecular Medicine


The Centre for Human Genetics and Molecular Medicine within the School of Health Sciences has been started with an aim to conduct multidisciplinary research in the field of Human Genetics. Research output from this centre will be having direct application in prediction, prevention and therapeutics of human genetic diseases, cancers and other ailments. At present the Centre is in infancy but it is the vision of the Centre to be a premier research unit in the country conducting and promoting groundbreaking research in human genetics. The centre has established state-of–the-art equipment facilities with a mission to offer molecular diagnostic, genetic and proteome profile of various genetic disorders. The centre is also gearing up to carry out prenatal diagnosis and newborn screening in the long run. We are also aiming to provide diagnostic services for congenital malformations and genetic disorders at the chromosomal, biochemical and molecular level. Counselling will be offered to the affected individuals and also their family members. Our aim is to prevent morbidity and mortality due to the genetic disorders and adult onset disorders. Currently different labs at this centre are working on some thrust areas like:

  1. Cancer biology and biomarker studies
  2. Structural and functional analysis of various proteins in human diseases
  3. Identification and characterizing modifier genes involved in disease onset and severity of various genetic disorders
  4. Identifying the susceptibility genes involved in the pathogenesis of the common chronic diseases
  5. Estimation of the risk confers by the genomic variations in different ethnic populations  
  6. Development of chimeric biomolecules as therapeutics

 

Faculty

  1. Prof. Anjana Munshi, Associate Professor, Centre Coordinator
  2. Dr. Preeti Khetarpal, Assistant Professor
  3. Dr. Sandeep Singh, Assistant Professor
  4. Dr. Harish Chandra, Assistant Professor
  5. Dr. Sabyasachi Senapati, Assistant Professor
  6. Dr. Neeraj Kumar , Assistant Professor
  7. Dr. Md. Noor Alam, Assistant Professor

Academic Programmes Offered

  • Ph.D. Human Genetics
  • Ph.D. Molecular Medicine
  • M. Sc. Life Sciences with specialization Human Genetics
  • M. Sc. Life Sciences with specialization Molecular Medicine
  • M.Sc. Human Genetics

Syllabi

  • M.Sc. Life Sciences with Specialization Human Genetics 2016-17
  • M.Sc. Life Sciences with Specialization Molecular medicine 2016-17
  • M.Sc. Life Sciences with Specialization Human Genetics 2015-16
  • M.Sc. Life Sciences with Specialization Molecular medicine 2015-16
  • M.Sc. Human Genetics 2014-15
  • Ph.D. Molecular Medicine
  • Ph.D.Human Genetics
  • Research Highlights

    1. Birth defects
    2. Haemoglobinopathies
    3. Stroke Genetics and Pharmacogenetics
    4. Genetic basis of infertility
    5. Bioinformatics, structural biology
    6. Cancer Biology
    7. Chemotherapy induced toxicity
    8. Signaling pathways during Inflammation and oxidative stress in various human diseases,
    9. Cancer cell migration and metastasis, monoclonal antibodies
    10. Immunogenetics of autoimmune diseases

    Laboratory Facilities

    The centre has two well-equipped laboratories with well-maintained basic laboratory equipment such as:

    • Ultra-low temperature freezers
    • High-speed centrifuges with a range of rotors
    • Shaking and cooled incubators
    • Microscopes
    • Water Bath
    • Water Purification system
    • Refrigerators
    • Sonicators
    • CO2  incubators
    • Laminar air flow cabinets
    • Tranilluminator

    High-end Equipment in the lab

    • BD Accuri™ C6 makes the analytical power of flow cytometry 
    • Gradient PCR machine
    • Qubit-Fluorometer
    • Muse Cell Analyzer

    Publications (2013-2015)

    Dr Anjana Munshi, Associate Professor, Centre Coordinator

    1. Dadheech S, Madhulatha D, Jain S, Joseph, J , Jyothy A, and  Munshi A. Association of BCL11A Genetic Variant (rs11886868) with severity in β-Thalassemia Major and Sickle Cell Anemia. Indian Journal of Medical Research(accepted for publication). (Impact factor: 1.66).
    2. Shaheen S , Jyothy A,  Hinore JS, Girdhar A, BandaruS, Sumithnath TG, Nayarisseri A and Munshi A. (2015) Computer aided identification of sodium channel blockers in the clinical treatment of epilepsy using molecular docking tools Bioinformation1 1(3) : 131-135.
    3. Munshi A, Das S, Kaul S (2015).Genetic determinants in ischaemic stroke subtypes: Seven year findings and a review Gene 555(2):250-259. Impact factor: 2.20.
    4. Prasad DK, Shaheen U, Satyanarayana U, Surya Prabha T, Jyothy A and Munshi A. (2014).Association of serum trace elements and minerals with genetic generalized epilepsy and idiopathic intractable epilepsy Neurochem Res. 39 (12):2370-6. Impact factor: 2.55.
    5. Jharna P ,Sukanya B,  Ajit Kumar ,SiddapuramSV, Jyothy A and  Munshi A. Apolipoprotein C3 gene polymorphisms in Southern Indian patients with nonalcoholic fatty liver disease Indian J Gastroenterol. 33(6):524–529.
    6. Amirisetty R,  Patel R P,  Das S,  Saraf J,   Jyothy A,  Munshi  A. (2014). Interleukin 1ß (+3954, -511 and -31) polymorphism in chronic periodontitis patients from North India Acta odontologica scandinavica DOI:10.3109/00016357.2014.961958. Impact factor: 1.41.
    7. Roy S, Das S,  Sharma V, Kaul S, Jyothy A, Munshi A. (2014). Association of -1382A>G CCL11 gene variant with ischemic stroke, its subtypes and hemorrhagic stroke in a South Indian Population Neurology India 62(4):387-392. Impact factor: 1.044.
    8. Das SRoy SSharma VKaul SJyothy AMunshi A. (2014). E-selectin gene (S128R) polymorphism in hemorrhagic stroke: comparison with ischemic stroke. Neuroscience letters 3; 581:125-128. Impact factor: 2.055
    9. Prasad DKV, Shaheena U ,Satyanarayana U,  SuryaPrabha  T, Jyothy A, Munshi A. (2014).  Association of GABRA6 1519 T>C (rs3219151) and Synapsin II (rs37733634) gene polymorphisms in thedevelopment of Idiopathic Generalized Epilepsy. Epilepsy Research 39(12):2370-2376. Impact factor: 2.241.
    10. Das S, Roy S, Sharma V, Kaul S,  Jyothy A, Munshi A. (2014). Association of ACE gene I/D polymorphism and ACE levels with hemorrhagic stroke: comparison with ischemic stroke Neurological Sciences DOI 10.1007/s10072-014-1880-8. Impact factor: 1.412.
    11. Das S, Roy S, Kaul S,Jyothy A, Munshi A. (2014). CRP Gene (1059G>C) Polymorphism and its Plasma Levels in IschemicStroke and HemorrhagicStroke in a South IndianPopulation Inflammation 37(5):1683-8 Impact factor: 2.46.
    12. Roy S, Das S, Danaboina R, Sharma V, Kaul S, Jyothy A and Munshi A. (2014).Association of E-selectin Gene Polymorphism (S128R) withIschemicStroke and StrokeSubtypes. Inflammation 37(2) 599-603. Impact factor: 2.46.
    13. Saudipopulation. Alharbi K K,  Khan  I A, Munshi A Alharbi  F K, Al-Sheikh  Y , Alnbaheen M S (2014) Association of the genetic variants of insulin receptor substrate 3 1 (IRS1) withtype 2 diabetes mellitus  Endocrine DOI 10.1007/s12020-014-0177-2. Impact factor: 2.25.
    14. Dadheech S, Jain S, Madhulatha D, Sharma V, James Joseph J, JyothyA, Munshi A. (2014) Association of Xmn1-158 γ G variant with severity and Hb Flevelsin β-Thalassemia major and Sickle cell anaemia Molecular Biology Reports 41 (5):3331-7. Impact factor: 2.51.
    15. ShaheenU,Prasad D K V ,Sharma V, Suryaprabha T, AhujaY R, Jyothy A ,  Munshi A. (2014) Significance of MDR1 gene polymorphism C3435T in predictingdrug response in epilepsy Epilepsy Research 108: 251-256 Impact factor: 2.24).
    16. Koppula R, Kaul S, Rao AV, Jyothy A, Munshi A. (2013). Association of serum uric acid level with ischemic stroke, stroke subtypes and clinical outcome Neurology Asia 18(4) : 349-353 Impact factor: 0.15.
    17. AlharbiKK , Khan I A,  , Al-daghri NM , Munshi A , Vandanasharma , Mohammed A K  , Wani K A , Al-sheikh1 Y A A ,  Salem al-Nbaheen M, Ansari2 M Gand and Rabbani S. (2013). ABCA1 C69T gene polymorphism and risk of type 2 diabetes mellitusin a Saudi population J. Biosci. 38(5): 893–897. Impact factor: 1.939.
    18. Sharma V,  Dadheech S, Kaul S, Jyothy A, Munshi A.(2013) Association of ALOX5AP1 SG13S114T/A Variant with Ischemic Stroke Stroke subtypes and Aspirin resistance. J Neurol Sci  331(1-2):108-13 Impact factor: 2.413.
    19. Sharma V,  Kaul S, Al-Hazzanid A, Alshatwi AA, Jyothy A, Munshi A. (2013). An association of COX-2 rs20417 with Aspirin resistance Thrombosis and Thrombolysis 35(1): 95-9. Impact factor: 1.985.
    20. Sneha D, Rao AV, Uzma, Hussien MD, Jain S,  A Jyothy, Munshi A.   (2013) Three most common non-synonymous UGT1A6*2 polymorphisms (Thr181Ala, Arg184Ser and Ser7Ala) and therapeutic response to deferiprone in β-Thalassemia Major patients. Gene. 531(2): 301.  Impact factor: 2.2.
    21. Munshi A, Prasoona R, Sunitha T, Jyothy A. (2013) Variants of DHFR, MTHsFD1 and MTHFR genes: Relation to CNS malformations Indian Journal of Obstetrics and Gynecology. 64 (1):24-25.
    22. SaiBabu M, Kaul S, Dadheech S, RajeshwarK,Jyothy A, and Munshi A. (2013). Serum albumin level in ischemic stroke and its subtypes: correlation with clinical outcome. Nutrition 29(6):872-875 Impact factor: 3.02.
    23. Munshi A, Satyanarayana U, Babu MS, Vasundhara A, Harischandra YV,  Krishna A, Kumari JS andJyothy A (2013). A novel LMNA mutation in two South Indian siblings with Hutchinson-Gilford progeria syndrome International Journal of Genetics 5(1):116-120 Impact factor: 7.05.

    Review Articles Published

    1. Association between PDE4D gene and ischemic stroke: Recent Advancements (2015) Das S, Roy S and Munshi A. The International Journal of Neuroscience May 23:1-17. [Epub ahead of print]. Impact factor: 1.528.
    2. Genetic Signatures in the Treatment of Stroke (2015) Munshi A, Sharma V. Current Pharmaceutical Design 21(3):343-54 Impact factor: 3.31).
    3. Genetics of idiopathic generalized epilepsy: An overview (2013) Prasad DKV, Satyanarayana U, Munshi A. Neurology India 61(6):572-577 Impact factor: 1.04).
    4. Genetic Modifiers of Β-Thalassemia-Review. (2013) Jyothy A, Munshi A. AP Academy of Sciences: Special Issue Women in Science 15(1): 23-27.
    5. Genetics of Non-alcoholic Fatty Liver Disease: an Overview (2013) Puppala J, Siddapuram SP, Jyothy A and Munshi A. Journal of Genetics and Genomics 40(1): 15-22 Impact factor: 2.9).

    Book Chapters Contributed

    1. Sharma S, Munshi A (2013). Omics approaches applications in Clinical Trials. Omics for Personalized Medicine (Springer) ISBN 978-81-322-1184-6 Chapter 7, pp 123-146.
    2. Munshi A, Ahuja YR (2013). Ethical Considerations in Pharmacogenomics. Omics for Personalized Medicine (Springer). ISBN 978-81-322-1184-6 Chapter 8 pp 147-162.
    3. Munshi A, Crotti LB, Vandana Sharma, Sanjeev Sharma, Luis A Espinoza(2013). Pharmacogenomics of Allergy and asthma. “Omics for Personalized Medicine” (Springer) ISBN 978-81-322-1184-6 Chapter 24, pp 529-560.
    4. Munshi A, Krupanidhi S and AhujaYR (2013) OMICS: Applications in Biomedical, Agricultural, and Environmental Sciences Epigenome. “Genomic response to environmental accentricities” (CRC Press, Taylor and Francis Group) ISBN: 978-1-4665-6281-3, Chapter 2, pp 44-63.
    5. Munshi A (2014). Nutrigenomics: Gene based personalized nutrition advice. Woman and Food studies from the Indian sub-continent. (Lambert Academic Publishing). ISBN-13: 978-3848430710, Chapter 17, pp 120-135.
    6. Munshi A, Sharma V (2014) Quality Control and Ethical Issues of Cancer Biomarker discovery. “Cancer Biomarkers: Non-invasive Early Diagnosis and Prognosis “(CRC press) ISBN: 978-1-4665-8428-0, Chapter 1, pp 3-15.
    7. Munshi A, Sharma V. Insilico Disease Models of Breast Cancer. "Omics Approaches in Breast Cancer :Towards Next-Generation Diagnosis, Prognosis and TherapyISBN-13: 978-8132208426, Chapter 16 (Springer) DOI 10.1007/978-81-322-0843-3_16
    8. Shafi G ,Hasan T N  , Syed NA, Paine A, Tegner J, Munshi A (2014).Breast Cancer MicroRNAs: Clinical Biomarkers for the Diagnosis and Treatment Strategies. “Omics Approaches in Breast Cancer: Towards Next-Generation Diagnosis, Prognosis and Therapy” ISBN-13: 978-8132208426 (Springer), Chapter 8 DOI 10.1007/978-81-322-0843-3_8.
    9. Munshi A, Ahuj Y. R,  Bir Bahadur(2015) Epigenetic Mechanisms in Plants: An Overview “Plant Biology and Biotechnology” (Springer)Chapter 12(final stage of publication).
    10.  Hasan TN, Shafi G, Grace L, Tegner J, and Munshi A (2015) DNA Methylation: An Epigenetic Marker of Breast Cancer Influenced by Nutrients Acting as an Environmental Factor.“Noninvasive Molecular Markers in Gynecologic Cancers”. ISBN 9781466569386 - CAT# K16436, Chapter 6(CRC Press, Taylor and Francis Group) pp187-206.
    11. Munshi A, Dadeech S, Babu S and Khetarpal P (2015). Modifiers of γ-globin gene expression and treatment of β-thalassemia. Inherited Disorders of Blood (Intech Publishers). Accepted for publication.

    Edited

    1. DNA Sequencing: Methods and Applications (Intech Publishers, Europe).
    2. Inherited Disorders of Blood (Intech Publishers, Europe) is being edited.

    Dr.Preeti Khetarpal, Assistant Professor
    Research Publications

    • Khetarpal P, Das S, Panigrahi I and Anjana Munshi.Primordial Dwarfism: Overview of Clinical and Genetic aspects Review Mol Gen Genom DOI: 10.1007/s00438-015-1110-y. Impact Factor::2.8

    Book Chapters

    • Munshi A, Dadeech S, Babu S and KhetarpalP(2015). Modifiers of γ-globin gene expression and treatment of β-thalassemia. Inherited Disorders of Blood (Intech Publishers). Accepted for publication.
    • Intellectual Property Rights in Animal Biotechnology- Book Chapter (Communicated)

     

    Dr. Sandeep Singh, Assistant Professor

    1. Qi Jing,  Singh S, Wei- Kai H, Qi C, Li L, YinWei H, Mcdonald T, Lin A, Guido M, Bhatia R, Chang C, Kuo YH. (2015) HDAC8 Inhibition Specifically Targets Inv(16) Acute Myeloid Leukemic Stem Cells by Restoring p53 Acetylation. Cell Stem Cells. Accepted for publication. Impact factor  22.2
    2. Joshi G, Singh S, Kumar R.  (2015) Growth factors mediated cell signalling in prostate cancer progression: Implications in discovery of anti-prostate cancer agents. Chemico-Biological Interactions. Accepted for publication. Impact Factor2.5
    3. Kumar R, Santos CD, Ahluwalia T and Singh S.  (2015) Signal Transduction Inhibitors as Promising Anticancer Agents," BioMed Research International. doi:10.1155/2015/584170 Impact Factor2.7
    4. Chauhan M, Rana A, Alex JM, Negi A, Singh S, Kumar R. (2014) Design, Microwave-mediated Synthesis and Biological Evaluation of Novel 4-Aryl(alkyl)amino-3-nitroquinoline and 2,4-Diaryl(dialkyl)amino-3-nitroquinolines as Anticancer Agents. Bioorg Chem. Nov.  Impact Factor2.9
    5. Ajit Vikram, Durga Nand Tripathi, Ashutosh Kumar, and Sandeep Singh,(2014) “Oxidative Stress and Inflammation in Diabetic Complications,” International Journal of Endocrinology, vol. 2014, Article ID 679754, 2 pages, 2014. doi:10.1155/2014/679754. Impact Factor1.5
    6. Kumar D, Kaur G, Negi A, Kumar S, Singh S and Kumar R. (2014)Synthesis and Xanthine Oxidase Inhibito ry Activity of 5,6-Dihydropyrazolo/pyrazolo[1,5-c]quinazoline Derivatives. Bioorg Chem.  Aug 30;57C:57-64.  Impact Factor2.9
    7. Alex JM, Singh S, Kumar R. (2014) 1-Acetyl-3,5-diaryl-4,5-dihydro(1H)pyrazoles Exhibit Anticancer Activity Through Intracellular ROS Scavenging and Mitochondrial Dependent Death Pathway.Arch. Pharm. Chem. Life Sci., 347, 1–11. Impact Factor1.5
    8. Dhar A, Mallick S, Ghosh P, Maiti A, Ahmed I, Bhattacharyya S, Mandal T, Manna A, Roy K, Singh S, Nayak DK, Wilder PT, Markowitz J, Weber D, Ghosh MK, Chattopadhyay S, Guha R, Konar A, Bandyopadhyay S, Roy S. (2014) Simultaneous Inhibition of Key Growth Pathways in Melanoma Cells and Tumor Regression by a Designed Bidentate Constrained Helical Peptide.Biopolymers. Apr; 101(4):344-58.. PMID: 24839139. Impact Factor2.9
    9. Qi J, Singh S, Cai Q, Li L, Liu H, Vu H, Huang WJ, McDonald T, Lin A, Chang CI, Bhatia R and Kuo YH.  (2013) Selective Targeting Of Inv(16)+ AML Stem Progenitor Cells By Inhibiting HDAC8. Blood. 2013; 122(21): 224. Impact Factor9
    10. Baviskar AT, Banerjee UC, Gupta M, Singh R, Kumar S, Gupta MK, Kumar S, Raut SK, Khullar M, Singh S and Kumar R. (2013) Synthesis of Imine-pyrazolopyrimidinones and their Mechanistic Interventions on Anticancer Activity. Bioorganic & Medicinal Chemistry.; 21(18): 5782-93. Impact Factor2.9

    Dr. Harish Chander, Assistant Professor

    1. Otto L D Cerqueria, Peter Truesdell, Tomas baldassare, Santiago A. Vllela-Arias, Kathleen Watt, Jalna Meens, Harish Chander, Cynthia A B Osorio, Fernando A Soares, Eduardo M Reis and Andrew WB Craig. (2015). CIP4 promotes metastasis in triple-negative breast cancer and is associated with poor prognosis.Oncotarget. 6: 9397-9408.
    2. Harish Chander*, Colin D Brien, Peter Truesdell, Kathleen Watt, Jalna Meens, Doris Germain and Andrew WB Craig*. (2014). Toca-1 is suppressed by p53 to limit breast cancer cell invasion and tumor metastasis. Breast Cancer Research. 16:3413 (December 30, 2014) (*Corresponding Author)
    3. Peter Truesdell, Joseph Ahn, Harish Chander, Jalna Meens, Kathleen Watt, Xialong Yang, Andrew W B Craig. (2014). CIP4 promotes lung adenocarcinoma metastasis and is associated with poor prognosis.Oncogene. (1 September 2014) | doi:10.1038/onc.2014.280). 
    4. Harish Chander, Jalna Meens, Peter Truesdell and Andrew W B Craig (2012). Transducer of Cdc42 actin assembly promotes breast cancer invasion and metastasis. Oncogene. 32:3080-3090.
    5. Harish Chander, Lois Resnick-Silverman, James J. Manfredi, Doris Germain. (2011). Skp2B overexpression alters a prohibitin-p53 axis and the transcription of PAPP-A, the protease of insulin-like growth factor binding protein 4. PLoS One,  6: 22456-22466

    Dr. Sabyasachi Senapati, Assistant Professor

    1. Senapati S, Gutierrez-Achury J, Sood A, Midha V, Szperl A, Romanos J, Zhernakova A, Franke L, Thelma BK, Wijmenga C, Trynka G (2015) Evaluation of European coeliac disease risk variants in a North Indian population.. Eur J Hum Genet. Apr;23(4):530-5. IF:4.2
    2. Juyal G, Negi S, Sood A, Senapati S, Gupta A, Prasad P, Singh S, Zaneveld J, Midha V, van Sommeren S, Weersma RK, , Ott J, Jain S, Juyal RC, Thelma BK (2014).Genome-wide association scan in a north Indian cohort identifies three novel HLA independent susceptibility loci in ulcerative colitis. GUT.  May 16. Pii: gutjnl-2013-306625 IF: 13.3
    3. Senapati S, Singh S, Das M, Kumar A, Gupta R, Kumar U, Jain S, Juyal RC, Thelma BK. (2014) Genome-wide analysis of methotrexate pharmacogenomics in rheumatoid arthritis reveals novel risk variants and leads for TYMS regulation. Pharmacogenetics and genomics. Apr;24(4):211-9. IF:3.5.
    4. Negi S, Juyal G, Senapati S, Prasad P Gupta A, Singh S, Kashyap S, Kumar A, Kumar U, Gupta R, Kaur S, Agrawal S, Aggrawal A, Ott J, Jain S, Juyal RC, Thelma BK. (2013) A genome-wide association study reveals ARL15, a novel non-HLA susceptibility gene for Rheumatoid arthritis in north Indians. Arthritis & Rheumatology. Dec; 65(12): 3026-35. IF:7.9

    Dr. Neeraj Kumar, Assistant Professor

    1. Kumar N, Jain V, Singh A, Jagtap U, Mukhopadhyay A. Genome-wide endogenous DAF-16/FOXO recruitment and topology of a conserved transcriptional response to lowered insulin signalling. Aging Cell (In communication) IF:6.34.
    2. Singh A, Kumar N, Matai L, Jain V, Mukhopadhyay A .­­­Feed-forward loops downstream of DAF-16/FOXO and PHA-4/FOXA regulate life span and development. Aging Cell  (In communication) IF:6.34.
    3. Pandit A, Jain V, Kumar N, Mukhopadhyay A. (2014) PHA-4/FOXA-regulated microRNA feed forward loops during Caenorhabditis elegans dietary restriction. Aging  Oct; 6 (10):835-855 . IF:6.34

    Papers Presented in Seminars/Conferences/Symposia/Workshops (2013-2015)

    Dr.Anjana Munshi

    • Genetic basis of Stroke on 8th November, 2014 in NeuroUpdate-2014 meeting at IICB (Indian Institute of Chemical Biology) Jadavpur, Kolkata.

    Dr.Preeti Khetarpal

    • Design and Trademark Registration on 23rd August, 2014 in Patent Awareness Workshop organized by PSCST, Chandigarh in IET Bhaddal, Ropar.
    • Introduction with IPRs and Patent system in India in Workshop on Advanced Research Methodology, Statistics and Patents in UGC-Academic Staff College, GNDU, Amritsar on 27th Sept, 2014.
    • Molecular Insights into Primordial Dwarfism on 6th Feb, 2015 in a conference DNA Diagnostics 2015 at PGIMER, Chandigarh

    Dr Sandeep Singh:

    • 1st North states conference on an anatomy of ageing: the need of focused research” held on August 25, 2012 at Department of Anatomy, Desh Bhagat Dental College & Hospital, Sri Muktsar Sahib. The title of the talk was “Cancer: relationship with ageing and free radicals.

    Dr. Harish Chander:

    • New Avenues in Breast Cancer at Association of Phrmaceutical teachers of India (APTI) 22nd-23rd August, 2014. Kurukshetra University, Haryana
    • Breast cancer Treatment and Mutations in Tumor Suppressor p53 at Association of Phrmaceutical teachers of India (APTI) 3rd-4th August, 2014. RayatBahra University, Hoshiarpur, Punjab

    Symposia/Workshops Organised by the Centre

    • One Day Symposium “Recent Trends in Molecular Medicine”: Dec 5, 2014
    • Workshop on Fluorescent in situ Hybridization (FISH) technique: 25-26 Sept, 2014.
    • World Cancer Day Symposia Recent Trends in Cancer Therapy:  Feb 4,  2014

     

    List of the Research Projects Operational in the Centre

    1. Munshi, A. “Amelioration of the Severity of β-thalassemia by Modifier Genes” funded by department of Biotechnology, Government of India, New Delhi (Rs. 37 Lac). (2013-16)
    2. Khetarpal, P. “Genetic investigations among Indian children with Silver Russell syndrome (SRS).” funded by University Grants Commission, New Delhi under Basic Science Research Start up Grant (Rs. 6 Lac). (2014-16).
    3. Munshi, A “The prevalence of thalassemia and mutation spectrum associated with the disease in Malwa Region of Punjab” funded by Central University of Punjab as Research Seed Money (RSM). (3 Lakhs)(2014-16).
    4. Khetarpal, P Cytogenetic investigations in couples of primary infertility from Malwa region of Punjab funded by Central University of Punjab as Research Seed Money (RSM). (3 Lakhs)(2014-16).
    5. Munshi, A. “In silico screening of all functional genes in human genome for the detection of deleterious SNPs for association studies” funded by Indian Council of Medical Research , Government of India , New Delhi (Rs. 38 Lac). (2015-18)
    6. Singh, S. “Genotoxicity of the pesticides used in Bathinda region” funded by University Grants Commission, New Delhi under Basic Science Research Start up Grant (Rs. 6 Lac). (2013-15).
    7. Singh, S. “Functional evaluation of presence of miRNAs inside the mitochondria of breast cancer cell lines”. funded by DST, New Delhi. (42 Lakhs)(2014-17).
    8. Singh, S. “Investigation of anticancer potential of Citrullus colocynthis extract” funded by Central University of Punjab as Research Seed Money (RSM). (3 Lakhs)(2014-16).
    9. Chandra, H. “Proteasomal mediated regulation of pro-metastasis protein Toca-1 in Breast Cancer” funded by Central University of Punjab as Research Seed Money (RSM). (3 Lakhs)(2014-16).

    Activities