School of Basic and Applied Sciences

Centre for Animal Sciences

The Center for Animal Sciences is created recently, which was originally a part of the Center for Biosciences (Established in 2009), is well-equipped with teaching and research laboratories. The center has vibrant and young faculty with national and international experience and expertise in frontier areas of basic and advanced research in animal biology. Faculty members cover wide area of research specialization from neuroscience to cancer biology to entomology. The quality of the faculty members is evidenced by their high impact publications (total no. of publications accounts to 82, with an impact factor of 353). The research programs of the faculty are supported by Grants from National and International Funding Agencies accounting to an amount of Rs. 2.95 crores.

Research thrust areas:

  1. Neurosciences
  2. Hormone-dependent development and plasticity of the adult brain
  3. DNA damage and repair
  4. Cancer Biology
  5. Basic and molecular entomology
  6. Insect vectors of human diseases
  7. Detection & Identification of Potential Biomarkers from Cancer

Faculty

  1. Dr. Anil K. Mantha, Associate Professor, COC
  2. Dr. Aklank Jain, Associate Professor
  3. Dr. Jyoti Parkash, Assistant Professor
  4. Dr. Krishna Chaitanya Rapalli, Assistant Professor
  5. Dr. Thamil Mani Sivanandam, Assistant Professor
  6. Dr. Sunil Kumar Singh , Assistant Professor
  7. Dr. Shahnaz Rahman Lone, Ramanujan fellowship

 

Academic Programmes Offered

The Centre for Animal Sciences offers the following programmes:

Syllabi

Research Highlights

The centre is currently engaged in the study of:

  • DNA damage-repair mechanisms in neuronal and non-neuronal cells; role of APE1 enzyme in various human diseases; development and characterization of plant based therapeutics aiming at functional modulation of APE1.
  • Hormone-dependent development and plasticity of the metabolic brain in physiological and pathological conditions.
  • Host-parasite interactions during transmission in the mosquito; and search of novel targets for effective insect-pest management.
  • To identify the potential biomarkers for cancer and determine their theraputic potential.

Laboratory Facilities

Centre for Animal Sciences features state-of-the-art laboratory with the latest scientific infrastructure. Among the high-end equipment are advanced gel documentation system, high speed refrigerated centrifuge, 2-D gel electrophoresis, inverted microscopes, humidified CO2 incubators, and -80o & -20o C deep freezers and animal tissue culture facility. In addition to its own facilities, other advanced facilities like Confocal Laser-Scanning Microscope with FCS, Field-Emission Scanning Electron Microscope, 96 capillary Automated DNA Sequencer and (FACS) are readily available through the Central Instrumentation Laboratory (CIL) at CUPB.

Equipment in Center

  • UV & Chemi-Documentation System (1 unit)
  • High Speed Refrigerated Table Top Centrifuge (1 unit)
  • High Speed Mini Centrifuge (1 unit)
  • 2-D Gel Electrophoresis System (1 unit)
  • 1-D Gel Electrophoresis System
  • Western Blotting (wet and semi-dry) System
  • Autoclave
  • Incubator Shaker (1 unit)                   
  • Stackable CO2 Incubator (3 units)      
  • Inverted Microscope (1 unit)         
  • Ice Flaking Machine (1 unit )                               
  • Water Distillation (1 unit)                  
  • - 80 OC Ultra Low Freezer (1 unit)
  • - 20 OC Low Freezer (1 unit)
  • 4 OC Refrigerator (4 units)
  • Spirometer (2 units)

List of the Research Projects Operational in the Centre:

Dr. Anil K. Mantha

Title of Project

Funding Agency

Grant Received

Identification of APE1-associated proteome during oxidative stress conditions in glioblastoma cell lines

Central University of Punjab, Bathinda
(2015-17)

Rs. 3 Lakhs

Mitochondrial Oxidative DNA Damage-Repair in Alzheimer’s Disease: AP-endonuclease (APE1/Ref-1) as a Potential Therapeutic Target

Dept. of Science & Technology (DST), New Delhi. (2014-17)

Rs. 46.6 Lakhs

Apurinic/Apyrimidinic endonuclease (APE1) as an anti-cancer therapeutic agent for Glioblastoma therapy

UGC, New Delhi under the BSR-start up grant scheme. (2013-15)

Rs. 6 Lakhs

Dr. Aklank Jain.

The Molecular Mechanisms of DNA Damage and Repair Induced by non-B DNA structures in Cancer

Department of Science and Technology (2012-2017

Rs. 83 Lakhs

Elucidating the role of potential miRNAs in the pathogenesis of Head and Neck Cancer

Department of Biotechnology (three years)

.Rs. 24.90 Lacks

(funds to be received)

Identification of circulating microRNAs as novel noninvasive biomarkers for early detection of lung cancer

ICMR (three years)

Rs. 32.70 Lakhs (funds to be received)

Development of vitamin receptor mediated endocytosis based biotin-irinotecan conjugates as selective and safer colon tumor targeting agents

Department of Biotechnology

Rs. 24.19 Lakhs

Co-PI

Dr. Jyoti Parkash

Role for Semaphorins and its Receptors in the Control of Sexual Brain Development and Adult Brain Plasticity 

UGC, New Delhi under the BSR-start up grant scheme. (2016-19)

Rs. 10 Lakhs 

Neural-glial-endothelial tripartite interactions: Unravel the basic cell-cell regulatory Mechanisms involved in the central control of reproduction.

SERB, DST India

2016-2019

Rs. 50.0 Lakhs 

Dr. Rapalli Krishna Chaitanya

Elucidation of the role of digestive proteases during Plasmodium transmission in Indian malarial vector, Anopheles stephensi  

DST-SERB

(2014-2017)

Rs. 16.5 Lakhs